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Scientists grow human intestine in the lab
Scientists have managed to grow a piece of human intestine in the laboratory, paving the way for new treatments for gut disorders such as Crohn's disease and even cancer.
The breakthrough was made using adult stem cells, which the researchers used to grow tissue fragments called organoids.
These are three-dimensional organ 'buds' with the potential to develop into tissues with certain functions.
They were then transplanted into mice, where they matured and each animal produced ‘significant’ amounts of fully functional human intestine.
The lead scientist, Dr Michael Helmrath, from the Intestinal Rehabilitation Programme at Cincinnati Children's Hospital in Ohio, said the breakthrough could have many implications.
‘This provides a new way to study the many diseases and conditions that can cause intestinal failure, from genetic disorders appearing at birth to conditions that strike later in life, such as cancer and Crohn's disease.
‘These studies also advance the longer-term goal of growing tissues that can replace damaged human intestine.’
It is hoped that one day, doctors will be able to grow organs as 'spare parts' using a patient's own cells, to repair tissue that is diseased.
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