KDOG: 100% success for the concept phase

March 25, 2017  21:48

Isabelle Fromantin, a nurse and doctor of science at the Curie Institute, presented with Dr. Séverine Alran, before the French National Academy of Medicine, the first scientific results attesting the reliability of the Kdog project, giving it a positive dynamic for the future of the program. The result of the two detector dogs, Thor and Nykios, participating in the sample detection tests, reaches 100% of success.​

After six months of training, Kdog finally reveals the results of these first tests, which prove its effectiveness.

The phase of samples recognition consists in two "passages" of the dog in front of the placed samples. By this we mean two exercises of sniffing the same samples interrupted by a pause. In the first pass, out of 31 patients sweat samples analyzed, 28 were detected positively by the dogs, which gives a result of 90.3% success. There is an evolution during the second pass of the dogs, with a rate of 100% success this time. The dogs were able to distinguish the healthy specimens and those with tumor markers.

This first stage of project validation consolidates the objectives of the project and confidently launches the clinical study that will start in 2018 on the same principles observed during this proof of concept phase.

She could present the results and perspectives of this promising and innovative project. First French nurse with a PhD in sciences and engineering, she is the spearhead of the Kdog project.

Kdog is a Canine Based Cancer Screening Research Program using a reliable, reproducible, non-invasive and inexpensive method that offers an alternative to mammography in first intention. Kdog is based on the work of Dr. Isabelle Fromantin, a nurse at the Curie Institute, on the wounds and healings of breast cancer. Dogs, at the heart of the detection process, are trained by dog experts who work on olfactory memorization at a very low threshold for detecting infected cells on tumor samples and then on wipes.​

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