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American and Japanese immunologists are awarded Nobel Medicine Prize for research for their work on cancer therapy
Two immunologists, James Allison of the US and Tasuku Honjo of Japan, won the 2018 Nobel Medicine Prize for research that has revolutionised the treatment of cancer, the jury said on Monday.
The pair were honoured 'for their discovery of cancer therapy by inhibition of negative immune regulation,' the Nobel Assembly said.
Immune checkpoint inhibitor therapy targets proteins made by some immune system cells, as well as some cancer cells.
The proteins can stop the body's natural defences from killing cancer cells.
The therapy is designed to remove this protein 'brake' and allow the immune system to more quickly get to work fighting the cancer.
In 2014 Professor Allison from the University of Texas, and Professor Honjo from Kyoto University won the Tang Prize which is touted as Asia's version of the Nobels.
The duo will share the Nobel prize sum of nine million Swedish kronor (about $1.01 million/ 870,000 euros/ £770,000).
They will receive their prize from King Carl XVI Gustaf at a formal ceremony in Stockholm on December 10.
This is the anniversary of the death of Alfred Nobel in 1896 who created the prizes in his last will and testament.
Last year, US geneticists Jeffrey Hall, Michael Rosbash and Michael Young were awarded the medicine prize for their research on the role of genes in setting the 'circadian clock' which regulates sleep and eating patterns, hormones and body temperature.
The winners of this year's physics prize will be announced on Tuesday, followed by the chemistry prize on Wednesday. The peace prize will be announced on Friday, and the economics prize will wrap up the Nobel season on Monday, October 8.
For the first time since 1949, the Swedish Academy has postponed the announcement of the 2018 Nobel Literature Prize until next year, amid a #MeToo scandal and bitter internal dispute that has prevented it from functioning properly.
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