Exposure to nicotine in a future father’s body may affect metabolism in his children and increase their risk of developing Diabetes Mellitus, according to a study published in the journal Journal of the Endocrine Society.

In the experiment, male laboratory mice were given nicotine in their drinking water. Researchers then observed the health of their offspring. The analysis showed that the young animals displayed changes in glucose metabolism and liver function, factors associated with the development of metabolic disorders.

Among female offspring, scientists recorded lower fasting insulin and glucose levels. Male offspring, in turn, showed changes in blood sugar levels and liver function compared with the control group. According to the researchers, such alterations may increase the risk of metabolic diseases, including Diabetes Mellitus.

The authors emphasize that the experiment was conducted on animals. Nevertheless, the findings highlight the important role of the health of future fathers. Researchers suggest that nicotine exposure before conception may have long-term consequences for the metabolic health of the next generation.

Earlier studies have also linked oral diseases such as Periodontitis with a higher risk of developing Diabetes Mellitus, Alzheimer’s disease, and Arthritis.