Japanese scientists have discovered that a compound called mitorubin can slow down the age-related decline of heart function and even partially restore it. This was reported by RIA Novosti, citing Professor Shigeru Yanagi of Gakushuin University.

The researchers studied the effects of mitorubin—an experimental substance derived from the natural compound berberine. The latter is already used in medicine and is found in plants such as barberry, common centaury, and the Amur cork tree. The drug was tested on mouse cells to understand its impact on cellular energy production.

According to the scientists, the number of mitochondria decreases with age and their functions weaken, which negatively impacts the condition of the heart muscle. The study showed that mitorubin increases the levels of MITOL molecules, which are responsible for the "quality control" of mitochondria, and helps increase their overall count.

As a result, the cells' ability to produce energy is enhanced. According to the experimental data, this helped slow the age-related deterioration of heart function and even led to a partial recovery of its performance.

However, the scientists emphasize that these results have currently only been obtained in animal models. Additional research will be required to confirm the effectiveness and safety of this method in humans.

The authors of the study note that the decline in mitochondrial activity is at the root of many age-related diseases. Further study of mitorubin could accelerate the development of new therapeutic approaches for cardiovascular disorders.