Polyphenols are special chemical compounds present in berries that can help preserve bone mineral density and reduce inflammation in bone tissue. This is the conclusion of a study by researchers from the Universities of Milan and Pavia, the findings of which were published in the journal Nutrients.

The researchers analyzed 19 previously published studies, including both clinical trials and experiments on animal and cell models. The main objective was to assess the effect of berry compounds on bone health.

In particular, anthocyanins were studied in detail, reports Planet Today. They are a type of polyphenol—natural antioxidants found in plants that help protect cells from inflammatory and oxidative stress. These compounds give berries their rich blue, purple, and red colors.

Previous research had indicated some positive effects of anthocyanins on bone mineral density. However, those studies were observational, and their findings varied in their consistency.

In laboratory experiments, a more pronounced effect was observed. Berry extracts were able to reduce the activity of osteoclasts, the cells that break down bone tissue. Also, they intensified the activity of osteoblasts, the cells involved in bone formation, and helped protect bones from inflammation and the effects of free radicals.

The researchers emphasize, however, that the evidence is still limited and further observations should continue and expand. In addition, berries cannot serve as a standalone treatment; they merely help make drug therapy more effective.