COVID-19 vaccination during pregnancy poses no additional risks to mother and child  

COVID-19 vaccination during pregnancy is associated with a lower risk of miscarriage, ICU hospitalization, and no additional health risks to the baby or the mother. These are the findings of a meta-analysis conducted by physicians from the University of Tsukuba and the Ohio Center for Cardiovascular Disease Research. The results of the study are published in JAMA Pediatrics.

The doctors analyzed nine observational studies comparing the pregnancy outcomes of 81,000 COVID-19 vaccinated women and 255,000 unvaccinated pregnant women.

98.2% of vaccinated patients received an mRNA vaccine (Pfizer/BioNTech, Moderna or other), as 1.1% received a vector vaccine (Oxford/AstraZeneca or Johnson & Johnson), and 0.7% received an unknown vaccine (data not shown).

COVID-19 vaccination during pregnancy was associated with a lower risk of ICU hospitalization, stillbirth, and maternal infection with SARS-CoV-2.

Significant additional risk of preterm birth, low Apgar score of newborns was not observed.

Moreover, the rate of preterm birth was lower in women who were vaccinated in the second or third trimester compared with women who were not vaccinated or vaccinated in the first trimester. 94% of women were vaccinated during the second or third trimester.

Thus, the scientists' data confirm the safety and effectiveness of COVID-19 vaccination during pregnancy.

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