Staphylococcus aureus may help SARS-CoV-2 multiply

January 20, 2023  14:41

Staphylococcus aureus in the laboratory helps SARS-CoV-2 virus multiply, scientists from the University of Western Ontario have found, iScience reported.

Staphylococcus aureus is often the cause of secondary bacterial infection in various acute respiratory infections. Previously, studies have shown that bacteria and viruses can interact at the molecular level, contributing to each other's reproduction.

In the new study, scientists analyzed the relationship between methicillin-resistant Staphylococcus aureus (MRSA) and SARS-CoV-2 (strain USA300 LAC) and found that the bacterium increased the rate at which the virus multiplied in epithelial cells by 10 times. At the same time, the virus had no significant effect on bacterial growth.

The genetic variant of Staphylococcus isdA provided a proviral effect for the bacteria. Drugs acting on products of this gene could disrupt the interaction between bacterial proteins and respiratory viruses. The results of the study are to be tested on living organisms.
 

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