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15:32, April 26 ESCMID: New method of purifying the air with ultraviolet light could protect world from new pandemic
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08:43, April 26 Enzymes that convert different blood groups into first group are discovered
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19:41, April 25 Children’s Hospital Los Angeles and International Center of Professional Development Allergy/Immunology Conference
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17:31, April 25 JAMA: patient grew long, curly eyelashes because of chemotherapy
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11:08, April 25 Mpox epidemic declared in Republic of the Congo
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01:20, April 25 Paralyzed man in China writes hieroglyphs using neural implants placed in his brain
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15:11, April 24 Zombie deer disease possibly linked to hunters’ deaths
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12:27, April 23 Appetite: Scientists found out the secret to the appeal of large portions of fast food
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10:33, April 23 Scientists test new approach to fighting viruses
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08:38, April 23 Ketamine may help with postpartum depression
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22:12, April 22 Unhealthy amount of sugar found in baby food products of a well-known brand
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19:41, April 22 Air pollution puts health of more than 1.6 billion workers globally at risk
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17:25, April 22 Scientists found baked goods and lack of sleep to be more dangerous than alcohol
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16:02, April 22 342 cases of measles recorded in Armenia so far in 2024
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Blue light exposure decreases systolic blood pressure, arterial stiffness, and improves endothelial function in humans
Aims
Previous studies have shown that ultraviolet light can lead to the release of nitric oxide from the skin and decrease blood pressure. In contrast to visible light the local application of ultraviolet light bears a cancerogenic risk. Here, we investigated whether whole body exposure to visible blue light can also decrease blood pressure and increase endothelial function in healthy subjects.
Methods
In a randomised crossover study, 14 healthy male subjects were exposed on 2 days to monochromatic blue light or blue light with a filter foil (control light) over 30 minutes. We measured blood pressure (primary endpoint), heart rate, forearm vascular resistance, forearm blood flow, endothelial function (flow-mediated dilation), pulse wave velocity and plasma nitric oxide species, nitrite and nitroso compounds (secondary endpoints) during and up to 2 hours after exposure.
Results
Blue light exposure significantly decreased systolic blood pressure and increased heart rate as compared to control. In parallel, blue light significantly increased forearm blood flow, flow-mediated dilation, circulating nitric oxide species and nitroso compounds while it decreased forearm vascular resistance and pulse wave velocity.
Conclusion
Whole body irradiation with visible blue light at real world doses improves blood pressure, endothelial function and arterial stiffness by nitric oxide released from photolabile intracutanous nitric oxide metabolites into circulating blood.
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