New method developed that detects unknown chemicals in human body

Today, many unknown chemicals pose potential risks. Recently, Chiba University (Japan) researchers developed a new analysis method for detecting such chemicals in the human body. The study was published in the journal Ecotoxicology and Environmental Safety, reports Phys.org

Using this method, the researchers analyzed serum samples from 84 pregnant women at 32 weeks of pregnancy. These samples were then examined using Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry.

The detected chemicals were classified based on their origin using the PubChemLite for Exposomics database, which contains information on over 371,663 chemicals.

Endogenous chemicals were identified as those naturally produced by the body and associated with biological pathways, while exogenous chemicals were categorized as substances introduced from external sources such as the environment, diet, or lifestyle.

The researchers identified 106 compounds, of which 51 were endogenous and 55 were exogenous. Most of the exogenous chemicals were found to have been introduced into the body through dietary sources.

Additionally, they found compounds associated with possible health risks, such as phthalates, nitrogenous compounds, and parabens.

Moreover, some of the chemicals identified were found to impact biological pathways, such as amino acid metabolism, protein and mineral transport, and energy metabolism.

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