Aging is the main risk factor for developing cancer, and as life expectancy increases, the proportion of people worldwide living with cancer is expected to rise. Researchers from the University of British Columbia and the University of Toronto have warned. The experts were quoted by The Independent.
According to the scientists, cancer risk increases with age largely because the body’s cells accumulate DNA damage and other abnormalities, while the mechanisms that control cell division gradually become less effective. At the same time, tissues become less capable of repairing themselves and eliminating damaged cells. As a result, the likelihood of cancerous cells emerging increases.
“Age affects not only the likelihood of developing the disease but also the ability to tolerate treatment. Older people are more likely to have comorbidities, cognitive impairment, reduced physical activity and other conditions that can alter the balance between the benefits and risks of chemotherapy, radiation therapy or surgery,” the experts said.
The scientists emphasize that the growing number of older people requires changes in the way cancer care itself is organized. A one-size-fits-all approach to cancer treatment may be ineffective for older patients, while assessing a person’s overall health and functional status can help doctors select treatment that takes into account not only life expectancy but also quality of life.
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