JAMA: high blood glucose levels may be a predictor of depression

High levels of glucose and triglycerides and low levels of high-density lipoproteins in the blood correlate with an increased likelihood of developing depression, anxiety and stress disorders. These conclusions were reached by scientists from the Karolinska Institute in Sweden as part of an international research team. They shared the results of the study in JAMA Network Open.

During the study, scientists measured the levels of glucose, triglycerides (fats, which are the body's main source of energy) and "good cholesterol" (high-density lipoproteins) in the blood of 211200 participants. This was followed by a period of observation of the subjects that lasted more than 20 years.

At the end of the observation phase, the researchers collected information about the mental health of the participants. It is noted that during this time, 16256 subjects were diagnosed with depression, anxiety or stress-related disorders. It turned out that low levels of "good cholesterol" in the blood in conjunction with an increased concentration of triglycerides and sugar correlated with an increased risk of developing these mental pathologies in both men and women.

According to scientists, metabolic dysregulation increases the likelihood of developing common psychiatric disorders. More research is needed to see if earlier interventions (e.g. dietary and medication) can neutralise this relationship.

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