Swedish doctors transplanted uterus of 9 women

January 14, 2014  19:26

In Sweden, nine women were successfully transplanted uterus from their relatives, and soon they will try to get pregnant, said the doctor, who is responsible for this innovative project, Fox News reports.

The women were born without a uterus or had it removed because of cervical cancer. Most are in their 30s and are part of the first major experiment to test whether it's possible to transplant wombs into women so they can give birth to their own children.

Life-saving transplants of organs such as hearts, livers and kidneys have been done for decades and doctors are increasingly transplanting hands, faces and other body parts to improve patients' quality of life. 

There have been two previous attempts to transplant a womb - in Turkey and Saudi Arabia - but both failed to produce babies. Scientists in Britain, Hungary, the U.S. and elsewhere are also planning similar operations but the efforts in Sweden are the most advanced.

"This is a new kind of surgery," Dr. Mats Brannstrom told The Associated Press in an interview from Goteborg.

Brannstrom, chair of the obstetrics and gynecology department at the University of Gothenburg, is leading the initiative. Next month, he and colleagues will run the first-ever workshop on how to perform womb transplants and they plan to publish a scientific report on their efforts soon.

He said the nine womb recipients were doing well. Many already had their periods six weeks after the transplants, an early sign that the wombs are healthy and functioning. One woman had an infection in her newly received uterus and others had some minor rejection episodes, but none of the recipients or donors needed intensive care after the surgery, Brannstrom said. All left the hospital within days.

The transplants have ignited hope among women unable to have children because they lost a uterus to cancer or were born without one. About one in 4,500 girls are born with a syndrome, known as MRKH, where they don't have a womb.

Dr. Richard Smith, head of the U.K. charity Womb Transplant UK, said the biggest question is how any pregnancies will proceed.

"The principal concern for me is if the baby will get enough nourishment from the placenta and if the blood flow is good enough," he said.

Brannstrom said he and his colleagues hope to start transferring embryos into some of their patients soon, possibly within months. 

After a maximum of two pregnancies, the wombs will be removed so the women can stop taking the anti-rejection drugs, which can cause high blood pressure, swelling and diabetes and may also raise the risk of some types of cancer.

"This is a research study," he said. "It could lead to (the women) having children, but there are no guarantees ... what is certain is that they are making a contribution to science."

Follow NEWS.am Medicine on Facebook and Twitter


 
  • Read also
 
  • Event calendar
 
 
  • Archive