The effect of certain drugs decreases or increases depending on the time of day - this is due, according to doctors, to the body’s natural biological rhythms. For example, drugs to lower blood pressure should never be drunk in the morning, Daily Mail reported.
Pills for pressure, as warned by employees of the University of Warwick (UK), is best to drink in the evening before bedtime. But in the morning, when blood pressure rises naturally, it is impossible to take drugs to reduce blood pressure.
‘We have clocks in our bodies that control most physiological processes,’ says Dr Robert Dallmann, assistant professor in molecular clocks at Warwick University Medical School. ‘They determine when we are active, when we rest, and how we metabolise drugs. As a result, some drugs are best given at night and others during the day.
Paracetamol is processed in the body by the liver. But the drug could be more toxic if taken in the morning. ‘Our levels of an enzyme called NAPQI in the liver are highest in the morning, and paracetamol increases this level,’ says Dr Dellman. ‘If this enzyme builds up, it can cause significant damage.